Alprostadil

Alprostadil is a drug for the treatment of erectile dysfunction (erectile dysfunction), available in Australian pharmacies for decades. Alprostadil has several distinctive features that make it different from any other drug for the erectile function recovery.

The main difference of Alprostadil from other medications is its release form.

Virtually all drugs for the erectile dysfunction treatment are produced in the form of tablets or capsules for oral use.
Alprostadil is the only drug that is produced in the form of:

  • Intracavernous injections (administered in the cavernous tissue).
  • Intraurethral cream or suppositories (introduced into the urethra).

The unusual release form is both an advantage and disadvantage of Alprostadil.

Advantages:

  • Because Alprostadil injected directly into the penis, it acts locally and helps achieve an erection in just 5 minutes after use.
  • Another Alprostadil advantage is that it starts working even without penis stimulation and sexual foreplay.

Disadvantages:

  • The main drawback of Alprostadil lies in the fact that the maximum duration of its effect is about 60-70 minutes.
  • Furthermore, Alprostadil can be used not more than three times a week. Therefore, men who were prescribed Alprostadil, can not plan the daily sexual activity.

Side effects can be included into the list of Alprostadil disadvantages. Regular injections administered in the cavernous tissue, or cream/suppository introduction into the urethra can cause pain/discomfort into the penis. These adverse reactions make many men refuse to use Alprostadil at an early stage of treatment.

Because of several serious flaws, Alprostadil is prescribed only when men are contraindicated to use such oral medications, as Sildenafil, Vardenafil, Avanafil, or Tadalafil.

Conventional oral tablets and capsules for the erectile dysfunction treatment are safer, easier and much more convenient to administer. Therefore, when men complain of weak or absent erections, doctors recommend starting treatment with the use of oral erectile dysfunction medications.

If a man can not take pills for the erectile dysfunction treatment, doctor has to make sure that the man does not have contraindications to Alprostadil, before he prescribes this drug.

  • The full list of contraindications to Alprostadil use is listed in the leaflet.

If you plan to start the erectile dysfunction treatment, read the leaflet and get reliable information about Alprostadil before you discuss your erection problems with a doctor.

If you have any questions about the erectile dysfunction treatment after reading the leaflet, ask your doctor or seek qualified pharmacist advice.If you have been prescribed Alprostadil, you can buy it in the city pharmacy networks or on the online pharmacies.

If you have no experience of intraurethral/intracavernous treatment of erectile dysfunction, your doctor will instruct you on how to inject Alprostadil.

Before issuing a prescription for Alprostadil, the doctor must teach his patient to make injections to himself or to introduce the drug into the urethra.Therefore, the first doses of Alprostadil are administered into the doctor’s office.

After the selection of the optimal Alprostadil dose, doctor may prescribe one or more doses of the drug.
The Australian pharmacies offer packages that contain:

  • Up to 6 doses of injectable Alprostadil.

Men who use this drug for a long-term erectile dysfunction treatment, should consult with their doctor every 3 months (or more often). If you plan to buy Alprostadil online without a prescription, and never used injection/cream for erectile dysfunction recovery, ask all your questions about Alprostadil to the online pharmacy pharmacist.

Alprostadil cream

Alprostadil cream: stable erection after the first application.

Alprostadil cream quickly eliminates potency problems and restores male sexual function. Europeans experiencing sexual dysfunctions can buy Alprostadil cream under the trademark Eafelb and use it to achieve erection as needed.

Eafelb has two dosage strengths – 2 mg / g and 3 mg / g of Alprostadil. Since 2015, the supplier of Eafelb cream is a global pharmaceutical company Ferring Pharmaceuticals. Each Eafelb pack contains four disposable tubes with Alprostadil cream.

Alprostadil creamShelf life:

  • Alprostadil cream 2 mg / g – 9 months
  • Alprostadil cream 3 mg / g – 18 months.

Eafelb – is not the only cream based on Alprostadil used in Europe to improve potency. Ferring company owns the marketing rights to Alprostadil cream called Vitaros.

Those men, who failed to buy Alprostadil cream, can find it in other countries under another trademark.

To solve sexual problems, Vitaros is used by men from many countries of Europe, including the UK, Ireland, the Netherlands, France and Portugal.

Dosage of Alprostadil cream

An initial dose of Alprostadil cream is matched individually for each patient depending on etiology and severity of potency disorders in men.

  • Alprostadil creamThe starting dose makes 200 mcg of Alprostadil
  • Patients with severe erectile dysfunction may start treatment with a dose of 300 mcg
  • The minimum interval between doses of Alprostadil cream should be about 24 hours
  • Health experts recommend to use Alprostadil cream no more than 2-3 times a week to restore potency in men
  • The maximum daily dose of Alprostadil cream makes 300 mcg.

The results of clinical studies confirm that the daily dose of Alprostadil 300 mcg cream helps to restore hardness of the male penis sufficient for full sexual intercourse. However, if this dose of Alprostadil cream causes side effects, it should be reduced to 200 mcg per day.

The minimal dose of Alprostadil 200 mcg cream helps significantly improve quality of erection and prolong sexual intercourse in men with erectile dysfunction caused by:

  • Increase of venous outflow in the cavernous bodies of the penis
  • Decrease in arterial blood flow to the male genitals.

At European pharmacies, one can buy Alprostadil cream under the brands Eafelb or Vitaros. These drugs for erectile dysfunction treatment are sold in disposable packs of 100 mg that contain 200 mg (2 mg / g) and 300 mg (3 mg / g) of active substance Alprostadil.

Dosage of Alprostadil injections

Injectable Alprostadil is one of the most effective drugs for treatment of erectile dysfunction in Australia.

Injectable Alprostadil helps to restore erection in men for about five minutes after administration in the erectile tissues of the penis.

Several set doses of injectable Alprostadil can be prescribed to men for quick restoration of erection and prolongation of sexual intercourse:

  • Alprostadil injectionsThe initial dose makes 2.5 micrograms per day.
  • The minimum therapeutic dose – is 5 micrograms per day.
  • The average doses of Alprostadil injections – is 10 mcg or 20 mcg in 24 hours.
  • The maximum daily dose makes 40 mcg.

The minimum set dose of Alprostadil 5 mcg injections is recommended to administer to patients with erectile dysfunction, which is caused by neurological disorders, such as:

  • multiple sclerosis
  • Parkinson’s disease
  • autonomic neuropathy
  • cerebrovascular accident.

Patients, whose inability to achieve or maintain an optimal degree of rigidity of the penis is not related to neurological dysfunctions, should use the average daily doses of Alprostadil injections 10 or 20 micrograms.

If erection is restored while using low doses of Alprostadil injections, but its hardness is not sufficient for a full sexual activity, subsequently the dose can be increased. A dose of Alprostadil injections should be increased in steps of 2.5 micrograms per day to a maximum of 40 mcg per day.

The optimal daily dose or a single dose of Alprostadil injections is that dose which helps to restore and maintain penile rigidity a maximum for one hour.

If penile rigidity persists for more than one hour when using the maximum dose of 40 mcg, it is necessary to reduce gradually the dose of Alprostadil injections by 2.5 micrograms daily.

In Australia, injectable Alprostadil is sold under the brand Caverject. The Australian supplier of this drug is a Pfizer.

Dose of intraurethral Alprostadil

Intraurethral sticks Alprostadil are developed specifically for adult men with erectile dysfunction by Meda company.

Compliance with dosage regimen of Alprostadil suppositories will help you regain an ability to achieve and maintain erection sufficient for sexual activity.

When choosing an adequate dose of intraurethral Alprostadil, it is necessary to take into account individual characteristics of every man with erectile dysfunction. There is a very high variability of patients’ personal parameters that can affect choice of intraurethral Alprostadil dose, ​​including:

  • erectile dysfunction etiology
  • The man’s age
  • Personal reaction to Alprostadil
  • Presence or absence of secondary diseases.

If you are using urethral suppositories Alprostadil for the first time, begin the treatment with the initial dose of 500 mcg. Further dose of this drug is determined in accordance with side effects and the man’s individual response to intraurethral Alprostadil:

If the man’s erection is restored when administering a suppository into the urethra, but adverse reactions occur, this dose of intraurethral Alprostadil should be reduced to 250 mg per day.

If intensity of adverse reactions is not reduced when administering this dose of urethral sticks Alprostadil, use the lowest dose of this drug – 125 mcg.

The maximum dose of intraurethral Alprostadil makes 1000 mcg used no more than once in 24 hours.

Alprostadil suppositories are intended exclusively for local use. To improve efficiency of intraurethral Alprostadil, do not divide the dose into several intakes per day.

  • To restore erectile function efficiently and safely, it is recommended to administer Alprostadil suppositories no more than three times a week.
  • To avoid overdose or adverse reactions of Alprostadil, administer into the urethra no more than one intraurethral stick per day.
  • To achieve a firm erection, the daily dose of Alprostadil should be administered once daily for about 10-15 minutes before the alleged sexual activity.

Alprostadil suppositories rapidly dissolve in the urethra under urine influence, so completely empty the bladder before their administration. Intraurethral Alprostadil is to be taken regularly, three times a week until complete restoration of erectile function.

In Europe, Alprostadil suppositories are sold under the brand Bondil. They are available as intraurethral sticks containing 125 mcg, 250 mcg, 500 mcg or 1000mcg of active ingredient Alprostadil and are sold in a kit with a disposable applicator.

Alprostadil for congenital heart defect

Before surgery to eliminate heart defect, functioning of the ductus arteriosus is necessary to provide.

Alprostadil – is a vasodilator drug, which is necessary for successful surgery.

In Australia, you can buy Alprostadil 0.5 mg / ml solution by several pharmaceutical companies.

Vasodilator means is to be used for infants with congenital heart defect to improve pulmonary blood flow before surgery.

Parents, whose children were born with congenital heart defect, can buy Alprostadil not only in Australia. This drug is available in many countries worldwide, including Europe.