Combined list of drug components for treatment of ED

Combined list of drug components for treatment of ED

The active ingredient is a substance that a pharmaceutical product contains. As of today, five active ingredients exist that are part of the drugs, approved for the treatment of erectile dysfunction (ED):

1. Sildenafil
2. Avanafil
3. Tadalafil
4. Vardenafil
5. Alprostadil.

In pure form, these substances are a white crystalline powder, which is used to produce ready-made dosage forms (tablets, capsules, jellies).

Different active ingredients have different chemical formulas:

  • Tadalafil – C22H19N3O4
  • Avanafil-C23H26ClN7O3
  • Sildenafil – C28H38N6O11S
  • Vardenafil – C23H32N6O4S.HCl.3H2O
  • Alprostadil – C20H34O5.

The first four ingredients belong to the pharmacological group of selective PDE5 inhibitors.

Ingredients from this group make part of popular branded drugs for ED treatment, such as:

  • Cialis (Tadalafil)

  • Viagra (Sildenafil)

  • Spedra (Avanafil)

  • Levitra (Vardenafil).

Alprostadil belongs to the prostaglandins group.

This active ingredient is part of the intraurethral medication for the treatment of ED, Muse, as well as intracavernous injections Caverject, Caverject Impulse and Edex.

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