Invicorp is a new injectable drug, approved for the treatment of erectile dysfunction.

Solution for injection Invicorp is sold in Europe since 2015. The European supplier of the new drug for the erectile dysfunction treatment is Evolan Pharma AB.

Invicorp differs from other injectable drugs for male potency enhancement by the fact that it comprises two active ingredients:

  • Aviptadil
  • Phentolamine.

Each of these ingredients alone has no effect on the male sexual function. But the combined impact of Aviptadil and Phentolamine over the cavernous tissue of the penis allows to quickly restore the ability to achieve and maintain an erection.

Just like other injectable medications for the treatment of erectile dysfunction (including Caverject), Invicorp can be used:

  • Not more than 1 time per day.
  • Not more than 3 times a week.

Failure to comply with the recommended frequency of Invicorp use increases the risk of severe adverse reactions, including priapism.

Invicorp injection should be administered in the cavernous tissue, and avoid inadvertent intravenous administration of the drug. To learn how to take Invicorp, you need to administer the first injections in the presence of a doctor.

The maximum duration of Invicorp effect is about 60 minutes. The ability to achieve and maintain an erection of the penis rigidity is lost in an hour after the administration of a single Invicorp dose.

Two key disadvantages of Invicorp injections are:

  • Short duration of action
  • Impossibility of daily use.

Two key advantages of Invicorp are:

  • Recovery of erection regardless of the erectile dysfunction cause
  • High efficiency in the treatment of severe erectile dysfunction.

Despite the fact that Invicorp drug has a small list of contraindications for use, only men, who can not use oral method of erectile function recovery, can get a prescription for Invicorp.

When the injection erectile dysfunction therapy is the only path to an active sex life, Invicorp can be a real solution for sexual problems.If conventional tablets or capsules for the treatment of erectile dysfunction are contraindicated to you, discuss with your doctor the possibility of using the injection method of sexual dysfunction treatment.

It is possible that after a consultation with your doctor, you will get a prescription for Invicorp, Caverject, Androskat or other injections, approved for the erectile dysfunction treatment in your country of residence.

Invicorp (Adaptivil/Phentolamine mesylate)


Invicorp Leaflet

Invicorp contraindications

Whom Invicorp is contraindicated?

Invicorp has a high safety profile, so it has a very small list of contraindications. Invicorp contraindications are the presence or a high risk of diseases associated with deformation of the male penis, including:

  • Angulation
  • Peyronie’s disease
  • Cavernous fibrosis.

When using Invicorp injections, the likelihood of priapism increases in patients with hematological diseases. In this regard, Invicorp is contraindicated to men with such risk factors of ischemic or non-ischemic priapism as:

  • leukemia
  • coagulopathy
  • multiple myeloma
  • sickle cell anemia
  • essential thrombocythemia.

Invicorp is also contraindicated in patients with implant in the penis. Because of the likelihood of drug interactions, Invicorp should not be used together with such erectile dysfunction treatment drugs, as Viagra, Stendra, Levitra, Muse, Caverject or Cialis.

Invicorp dosage

The recommended dosing regimen of Invicorp.

Invicorp is a second-line drug for treatment of erectile dysfunction produced exclusively in the form of solution for intracavernous injections. Each Invicorp ampoule contains 0.35 ml of the solution, which includes the following doses of active ingredients:

  • Aviptadil – 25 mcg
  • Phentolamine mesylate – 2 mg.

The dosage of 25 mcg / 2 mg is the only therapeutic dose of Invicorp approved for erectile dysfunction treatment.

  • The maximum dose of Invicorp for recovery of penile rigidity is 25 mcg / 2 mg.
  • Invicorp 25 mcg / 2 mg dose should be used no more than three times a week for safe and effective restoration of male potency.

Results of clinical studies confirm that dose adjustment of Invicorp is not required when treating erectile dysfunction in patients over 75 years old or those with comorbid conditions such as:

  • renal failure
  • liver disease.

Invicorp dose contained in the vial is calculated exclusively for a single injection. Do not divide the single daily dose of Invicorp 25 mcg / 2 mg into 2 or more intracavernous injections.

Invicorp side effects

Invicorp adverse reactions review.

Results of Invicorp clinical studies confirm that approximate frequency of adverse reactions of this drug for erectile dysfunction treatment is 10%.

The most common adverse reactions of Invicorp are hot flashes that are mild and transient. This undesirable phenomenon of Invicorp is sometimes difficult to distinguish from hot flashes during sexual arousal.When occurring some adverse events of Invicorp, patients are advised to discontinue using this erectile dysfunction treatment drug.

The reason for Invicorp cancellation can be such side effects as:

  • Chest pain
  • Anxiety
  • Myocardial infarction
  • Labored breathing.

Data of clinical studies show that one out of 1,000 men, Invicorp may cause priapism. Painful erection lasting more than 4 hours is among the most severe side effects of Invicorp.

In repeated administration of Invicorp, small seals may appear on the penis

Other rare side effects of Invicorp are:

  • headache
  • dizziness
  • pain in the left hand.

Very rarely, Invicorp may cause such cardiovascular side effects as:

  • tachycardia
  • angina
  • heart palpitations.

In inaccurate or incorrect administration, Invicorp may cause injuries or hematomas at the injection site.

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