Levitra is an oral tablet, which stands at the third position in the ranking of best medicines for the treatment of male sexual dysfunction. In 2017, Levitra pills are sold in almost every country of the world, including Australia.
- In the period of 2010 to 2013, only conventional Levitra tablets were available on the international market
- In September 2010, a new dosage form of Levitra went on sale, which is the orally dispersible tablets.
New Levitra works the same, as the conventional tablets, yet it has two important advantages. Since orally dispersible Levitra tablets dissolve in your mouth:
- You do not need water to wash them down – so you can take them without letting your sexual partner notice it.
- They get into your stomach in form of solution, so they do not cause gastrointestinal side effects.
The composition of new Levitra includes a sweetener, which masks the bitter taste of the active ingredient Vardenafil, and makes pills for erectile dysfunction treatment taste like simple candy.
Dosage of the active substance Vardenafil in one Levitra pill is indicated in milligrams (mg). In 2017, the pharmaceutical market can offer you:
- Conventional Levitra tablets of 5mg, 10mg, and 20mg.
- Orally dispersible Levitra tablets of 10mg.
Men who plan on taking Levitra for the first time, can buy a package that contains only one tablet for the erectile dysfunction treatment. A single dose Levitra pack is convenient for those men, who want to make sure that these tablets for the treatment of erectile dysfunction:
- really work
- cause no side effects.
Once you make sure that this drug helps to quickly and safely restore your erectile function, you can buy a large pack of Levitra that provides enough pills for a few months of treatment.
Efficacy and safety of Levitra:
- are proven by the results of preclinical and clinical studies.
- are confirmed by the members of Therapeutic Goods Administration (TGA).
The results of post-marketing observations show that Levitra helps to successfully treat different types of erectile dysfunction at any age, including simultaneously with the treatment of other diseases.
Levitra tablets have virtually no contraindications. Yet, before you take the first dose of this medication, you must thoroughly read the leaflet.
If you plan to buy Levitra online, read the electronic version of the leaflet for this product right now.
Information about Levitra is available in different languages, including English.
How does Levitra work?
The action mechanism of Levitra (Vardenafil) is based on the increase of blood flow to the penis. Because Levitra pills improve the hemodynamics in cavernous tissue of the penis, men manage to get an erection, sufficient to begin and successful complete a sexual intercourse.
Levitra tablets begin working within 30-60 minutes after the administration. However, the manufacturer recommends taking them at least 1 hour before the planned sexual activity.
The Australian manufacturer and supplier of Levitra is Bayer. Even before the launch of Levitra sales in Australia, Bayer assumed that it will be able to compete successfully with other manufacturers of drugs for the erectile dysfunction treatment, such as:
- Lilly (manufacturer of Cialis)
- Pfizer (manufacturer of Viagra).
Despite the fact that Levitra works just like Viagra and Cialis do, Bayer Company failed to conquer Australian market of drugs for the erectile dysfunction treatment. Today, the global sales of Levitra amount to about 110 million USD. This figure is only 5% of the global sales of the absolute market leader – Cialis tablets.
Levitra sales are down, and the trend of decline will increase after the appearance of the first Levitra generics in Australia. If Bayer Company and its partners fail to stimulate the sales growth of original Levitra pills, the competitive pressure from generics can force Bayer to stop the production of its drug for the treatment of erectile dysfunction.
A key partner of Bayer is GlaxoSmithKline (GSK). In 2005, Bayer and GSK companies reached an agreement to jointly commercialize Levitra tablets. Under the terms of the agreement, GSK received exclusive rights for the supply of Levitra in more than 20 countries worldwide.
- It should be noted that Bayer sells Levitra counterparts under different trademarks many years in a row.
- In the US, a 100% Levitra analogue is sold under the brand Staxyn, and in Europe – under the brand name Vivanza.
Levitra generics (analogs) that contain the active ingredient Vardenafil, are produced not only by Bayer, but by other pharmaceutical companies, as well. Until 2019, Levitra formula is protected by a patent, so the access of generics to Australia market is still closed.
Today, the only place where men can buy Levitra generics is an online pharmacy. However, in 2018-2019, cheap Levitra generics will appear in every Australian drugstore. Therefore, they will be available for purchase and use for the erectile dysfunction treatment not only by the online pharmacies visitors, but by every man, who can get a prescription for them.
As long as Levitra is sold in Australia only on prescription, men who are not willing to discuss their sexual dysfunction with their doctor will continue ordering their delivery on the Internet.
It only takes a few minutes to buy Levitra without prescription. Therefore, when they have to choose between a waste of time and money for doctor’s consultation and the online purchase of Levitra pills, 90% of men choose online drugstores.
Today, Levitra orodispersible tablets are available for sale in Australia, in addition to Levitra film-coated tablets. On April, 2003, Levitra tablets were approved for erectile dysfunction treatment in Australia.
The Australian supplier of Levitra tablets for treatment of male erectile dysfunction is a pharmaceutical company Bayer.
In Australian Register of Therapeutic Goods, Levitra tablets are registered under the ARTG ID:
Levitra orodispersible tablets include excipients that provide rapid tablet dissolution in the mouth. Due to the high rate of dissolution, dispersible tablets begin working faster than conventional Levitra tablets that dissolve in the stomach.
Levitra mechanism of action
Currently, first-line drugs that are used for the treatment of erectile dysfunction, are inhibitors of the enzyme phosphodiesterase type 5 (erectile dysfunction). One of the most famous and effective medications is considered Levitra.
The action mechanism is based on the blockage of Levitra erectile dysfunction enzyme, which takes an active part in the process of erection. Currently, the medical practice differentiates 11 groups of the enzyme phosphodiesterase, which are located in various cells of the body.
The active ingredient – Vardenafil – has a high selectivity for Perectile dysfunction type 5, which contributes to a good drug tolerability and reduces the incidence of side effects.
Studies have shown that one of the causes of a weak erection is the violation of the arterial blood influx into the cavernous bodies of the penis.
It is known that erectile dysfunction, localized predominantly in the cavernous tissue and smooth muscle cells of blood vessels, is capable of destroying cyclic guanosine monophosphate (CGMP) and reduce vascular tone.
CGMP is a versatile intracellular regulator and at the same time a nitric oxide (NO) mediator, which is essential for the erection. By inhibiting erectile dysfunction enzyme, Levitra maintains a high CGMP concentration and enhances the vasodilatory effect of NO.
Due to the administration of Levitra (Vardenafil):
- muscle layer of the penis relaxes;
- blood flow to the sexual organs increases;
- spongy erectile tissue fills with blood;
- erection sufficient for a satisfactory sexual performance is achieved.
Levitra is positioned as medication that has a more favorable pharmacokinetic profile. Compared to other erectile dysfunction inhibitors, the effectiveness of the drug does not depend on the consumption of alcohol and foods.
Contraindications to the use of Levitra pills.
Levitra tablets are contraindicated to patients with hypersensitivity to its active ingredient Vardenafil or one of inactive components of this drug for potency increase.
Patients with a history of such cardiovascular diseases as myocardial infarction or stroke are contraindicated to use Levitra for six months after the last cardiovascular event.
This drug for erectile dysfunction treatment does not have a strong influence on the heart or kidneys function. However, sexual activity can be contraindicated to certain groups of patients.
For this reason, the US health experts do not recommend taking Levitra pills for men with such diseases as:
- severe renal insufficiency
- aggravation of coronary heart disease
- primary pigmentary retinal dystrophy.
Levitra does not affect female sexual function, so women should choose alternative methods of increasing the level of sexual activity.
The recommended Levitra dosage to improve erection.
Drug therapy of erectile dysfunction should be started with a dose of Levitra 10 mg.
Depending on the clinical response; this average therapeutic dose of Levitra can be adjusted:
- In poor response to the average dose of Levitra 10 mg, it can be increased up to a maximum dose of 20 mg per day.
- If the starting dose of Levitra 10 mg works, but causes side effects, the subsequent doses can be reduced to 5 mg or 2.5mg per day.
To restore and improve quality of erection, take one Levitra tablet no more than once daily. If the dose was chosen correctly, the man will retain the ability to achieve erection within 36 hours.
If you take Levitra pills on an empty stomach, they will begin to work within 30-60 minutes. If erectile dysfunction treatment pills are taken after eating, onset of Levitra action may increase.
Levitra 5 mg
One Levitra 5 mg tablet – is the minimum therapeutic dose required to achieve and maintain an erection. Low dose of 5 mg is recommended to prescribe for treatment of sexual dysfunction in men:
- over 65 years
- with creatinine clearance less than 30 mL per minute
- with mild or moderate impaired hepatic function.
In addition, the minimal dose of Levitra 5 mg should be taken in simultaneous use of this drug for erectile dysfunction treatment with such drugs as Clarithromycin or Erythromycin.
The manufacturer of Levitra 5 mg – Bayer company produces this drug in the form of orange film-coated round tablets.
Each tablet is marked on both sides:
- “5” on one side
- Bayer’s corporate logo – on another.
Levitra 5 mg is available in aluminum blisters that can contain different number of tablets: 2, 4, 8, 12 or 20 pieces. The blisters are packed in cardboard boxes of white, orange and purple.
Levitra 10 mg
Buy Levitra 10 mg tablets.
Levitra 10 mg – is a usual therapeutic dose recommended for treatment of erectile dysfunction. To restore an ability to get an erection, men can use:
- Conventional pills Levitra 10 mg
- Orodispersible tablets Levitra 10 mg.
If the dose of 10 mg is not sufficient for successful intercourse, the next dose of Levitra can be doubled (up to 20 mg).
Men with impaired liver function should not take more than one Levitra 10 mg pill per day. Excess of dosage can lead to hepatotoxicity and other undesirable reactions.
- Conventional pills Levitra 10 mg come in packs of 2, 4, 8, 12 or 20 pieces. Levitra 10 mg oral tablets debossed «Bayer» on one side and “10” – on the another.
- Orodispersible tablets come in packs of 1, 2, 4 or 8 pieces. Original dispersible tablets Levitra 10 mg are not marked.
A German pharmaceutical company Bayer is the manufacturer and Australian supplier of Levitra 10 mg tablets.
Conventional pills Levitra 10 mg came into the market on August, 2003. Levitra 10 mg tablets are sold not only in Australia but also in most other countries.
Levitra 20 mg
Levitra 20 mg in the Australia.
The maximum dose of Levitra 20 mg is prescribed to patients with a low clinical response to the average or minimal dose of this drug for erectile dysfunction treatment.
Effect of one Levitra 20 mg dose lasts up to 36 hours. By increasing the dose up to 40 mg or more, the duration of Levitra effect is not increased.
When using the maximum dose of Levitra 20 mg, risk of adverse reactions may increase in some groups of patient.
In this regard, Levitra 20 mg is not recommended for men with moderate disorders of:
- kidney function
- liver function.
Orange Levitra 20 mg tablets have a film coating, which provides an optimum rate of release of the active ingredient Vardenafil.
Original Levitra 20 mg tablets are packaged in aluminum blister and cardboard box. Packaging containing 2, 4, 8 or 12 Levitra tablets are available for sale.
Levitra side effects
Levitra: side effects in details.
When following the dosage and all recommendations for Levitra use, side effects are not clinically significant and are mild to moderate.
Men treating erectile dysfunction by means of Levitra may experience:
- nasal congestion
- increased heart rate or
Adverse reactions may occur after the first application, as well as in regular use of Levitra.
Side effects may worsen as a result of:
- noncompliance with the dosage and recommendations for use
- low adherence to erectile dysfunction treatment
- irrational use of Levitra.
A small number of Levitra side effects is explained by high selectivity of the drug action. The drug inhibits only Perectile dysfunction-5 enzyme, which affects blood flow to the penis. Herewith, Levitra has no effect on other organs and systems, whose functions are regulated by erectile dysfunction.
Levitra generics: alternative to erectile dysfunction drug.
Generic Levitra is sold in the USA under the brand Staxyn. Also in 2015, preliminary approval for sale of Levitra generic drugs under the nonproprietary name Vardenafil was received by the following companies:
- Par Pharm.
The original drug Levitra and its generics have the same dosage form and strength of active ingredient Vardenafil. Levitra generic drugs are produced in the form of:
- conventional tablets containing 5, 10, and 20 mg of active substance Vardenafil
- orodispersible tablets containing 10 mg of Vardenafil.
Levitra and its generic Staxyn are produced by the same manufacturing company Bayer. In 2010, this company received the first marketing authorization for generic Levitra in the United States. GlaxoSmithKline (GSK) Corporation supplies Staxyn on the US market. In First Half 2017, Levitra generics are not sold in Australia.